Paper Example on Hypovitaminosis D and Vitamin D

Hypovitaminosis D and Vitamin D insufficiency refer to the poor performing level of the serum. The hypovitaminosis D is generally defined for serum level of 25 (OH) D that is below 30 ng/ ml. The high prevalence of hypovitaminosis D causes the depletion for muscle function that increases the risk of falls for such elderly group of people.

Clearly, Vitamin D plays an important role in the metabolism of calcium and phosphorus for human beings. However, following the depletion of the body systems, especially the digestive, renewal and skeletal systems the full metabolism occurs hence the fatigue. Arguably, the vitamin D endocrine systems play a central role in the skeletal and homeostatic integrity for the development of the relevant tissue system. The source of la25(OH)2D originates from the substance within a group of secosteroids called vitamin D2 that occurs naturally for self-synthesis for the skins that are called vitamin D3. The synthesis the skin is exposed to have an ultraviolet light that can be used to synthesize the vitamin D3 BY THE LACK of the cholecalciferol that has an abstract definition of a vitamin.

Objectives and Justification of the StudyBefore we proceed with the objectives, it is worthwhile to appreciate that the occurrence of fatigue because of hypovitaminosis is heavily triggered by inflammation (Knutsen and Valebjorg, 167). Non-communicable diseases such as COPD, HIV, and Aids, Cancer are said to induce a heavy degree of fatigue. These diseases are known to emit radicals in the body. For elderly people, their fatigue experience is naturally comparable to the patient with chronic for fatigue syndrome. The severe fatigue is naturally associated with problems of concentration and motivation. These problems are said to cause reduced physical activities as well a number of emotional health problems, common with fatigue. As other parallel complications prevail, such as fatigue, depression, and anxiety we witness modalities of treatment for time since treatment. Hence, as far as the objectives are concerned, we will be investigating the close relationship between hypovitaminosis and fatigue, closing noting the presence of inflammable disease because this is the bottom-line.

Explore occurrence of fatigue in elderly hypovitaminosis

Determine the relationship of the flammable diseases and their influence on the growth of hypovitaminosis

Establish the age variable and its relevance for understanding the occurrence of hypovitaminosis

Justify that fatigue is generally because of the presence of hypovitaminosis.

Materials and Methods

Literature ReviewResearchers have proved that at least one billion people could be suffering from hypovitaminosis D globally. However, the presence of hypovitaminosis D in elderly patients is caused by the possible prolonged periods. Most of these patients suffer prolonged illnesses such as cancer, and diabetes is naturally hospitalized for long periods and is known to be suffering from some sought of deficiency. The 25-hydroxyvitamin ionized calcium and parathyroid hormone require more vitamin D. The adult's Several researchers have agreed that different biochemical disturbances of the calcium and phosphates The research by Brock et al. (219) provide a deeper assessment of the utility of the Meta-analysis to explore the impact of fatigue on elderly women. Research has proved that hypovitaminosis D results from the alteration of metabolism for vitamin D for hepatic and kidney failure.

Research by Plotnikoff (1467) indicates, the high prevalence of hypovitaminosis D is an elderly population that is explained with the choice of hypovitaminosis and vary gradually based on sex and age. The research by Williams et al., first study explores known determinants of vitamin D status that provides a better assessment to the presence of vitamin D status for the East Asian Immigrants. The vitamin D supplements depend naturally on the sunlight exposure. Boucher (70) explores the interrelationship of diabetes and the development of the vitamin D complications presumably noting the utility of insulin enhancers. The Journal notes that vitamin D formed skin creates a bright sunshine for scarce foodstuff. The data linking with hypovitaminosis D results to cardiovascular risk for accumulated for sometimes. Researchers exploring fatigue levels have failed to understand the essence of the hypovitaminosis D myopathy (HDM) which is considered a cancan affected by hypovitaminosis D are older adults who are hospitalized.

Research by Khawaja (173) proves, the high prevalence rates is due to the increasing frequency rates that lead to the fundamental loss of functionality. Symptoms that are seen in patients suffering some problems of osteomalacic bone disease. The biopsy proven is found for sympathy that presents the different symptoms for clinically for detectable 96.7%. Hypovitaminosis D is naturally a misdiagnosed given the poor understanding of the gradual process that leads to the functional ability for quantification. The reason for missing diagnosis for the different symptoms for the different unspecific muscle pain, parenthesis and bone pain. The vitamin D receptor (VDR) is enabled for vitamin D medication for muscular effects for the novel protein, which are believed to stimulate synthesis for different proteins. Other researchers have explored the classical functions for bone metabolic regulation based on the vitamin D exhibitions for multiple biological targets for mediated hormone receptors.

Research explains that the central nervous systems depend on the entrance of Vitamin D for cerebrospinal fluid that involves the crossing of the blood-brain barrier as well as the different capillarity for blood. The CSF naturally correlates with the scrum for the various physiological conditions. In this case, the vitamin D experts for the different actions that revolves around nuclear hormone reception and is expressed with the different neuronal and gill cells. Rodriquez et al., (309) further notes that the binding of vitamin D and the VDR naturally triggered a neuronal protection that is attached against various degenerative procedures, which includes anti-inflammatory actions and various anti-oxidations. In this case, the blood tries to enhance the regulation of vitamin D that is involved in the regulation of the gene expression for numerous neurotransmission for the brain that includes serotonin and dopamine ef...